[Genetic polymorphisms of IL-28B are associated with sustained virologic response in patients with chronic hepatitis C].

doi:10.3760/cma.j.issn.1007-3418.2012.12.004

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Article

[Genetic polymorphisms of IL-28B are associated with sustained virologic response in patients with chronic hepatitis C].

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology - 1 Dec 2012

Xie Jun-qiang, Guo Xiao-yan, Cao Hong, Zhang Xiao-hong, Xie Dong-ying, Gao Zhi-liang, Zhao Zhi-xin

Abstract excerpt

OBJECTIVE: To explore the relationship between polymorphism in the interleukin (IL)-28B gene and sustained virologic response (SVR) in chronic hepatitis C (CHC) patients. METHODS: A total of 220 patients with CHC were prospectively treated with pegylated-interferon (peg-IFN) in combination with ribavirin (RBV) for 48 weeks, and followed-up for an additional 24 weeks. All patients were genotyped for the rs8099917...

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PMID: 23522248
DOI: 10.3760/cma.j.issn.1007-3418.2012.12.004

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