Article
Missense substitutions reflecting regulatory control of transmitter phosphatase activity in two-component signalling.
Molecular microbiology - 1 May 2013
Huynh TuAnh Ngoc, Noriega Chris E, Stewart Valley
Abstract excerpt
Negative control in two-component signal transduction results from sensor transmitter phosphatase activity for phospho-receiver dephosphorylation. A hypothetical mechanism for this reaction involves a catalytic residue in the H-box active-site region. However, a complete understanding of transmitter phosphatase regulation is hampered by the abundance of kinase-competent, phosphatase-defective missense...
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