Article
Crystal structure of the C-terminal domain of the two-component system transmitter protein nitrogen regulator II (NRII; NtrB), regulator of nitrogen assimilation in Escherichia coli.
Biochemistry - 1 Jun 2004
Song Yuanda, Peisach Daniel, Pioszak Augen A, Xu Zhaohui, Ninfa Alexander J
Abstract excerpt
The kinase/phosphatase nitrogen regulator II (NRII, NtrB) is a member of the transmitter protein family of conserved two-component signal transduction systems. The kinase activity of NRII brings about the phosphorylation of the transcription factor nitrogen regulator I (NRI, NtrC), causing the activation of Ntr gene transcription. The phosphatase activity of NRII results in the inactivation of NRI-P. The...
Topics
- Adenosine Triphosphate
- Amino Acid Sequence
- Bacterial Proteins
- Crystallography, X-Ray
- Escherichia coli Proteins
- Models, Molecular
- Molecular Sequence Data
- Mutation
- PII Nitrogen Regulatory Proteins
- Phosphoprotein Phosphatases
- Protein Conformation
- Protein Kinases