Article
Copy number variation prevalence in known asthma genes and their impact on asthma susceptibility.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Apr 2013
Rogers A J, Chu J-H, Darvishi K, Ionita-Laza I, Lehmann H, Mills R, Lee C, Raby B A
Abstract excerpt
BACKGROUND: Genetic studies have identified numerous genes reproducibly associated with asthma, yet these studies have focussed almost entirely on single nucleotide polymorphisms (SNPs), and virtually ignored another highly prevalent form of genetic variation: Copy Number Variants (CNVs). OBJECTIVE: To survey the prevalence of CNVs in genes previously associated with asthma, and to assess whether CNVs represent...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.