Article
Plasma carotenoid- and retinol-weighted multi-SNP scores and risk of breast cancer in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 May 2013
Hendrickson Sara J, Lindström Sara, Eliassen A Heather, Rosner Bernard A, Chen Constance, Barrdahl Myrto, Brinton Louise, Buring Julie, Canzian Federico, Chanock Stephen, Clavel-Chapelon Françoise, Figueroa Jonine D, Gapstur Susan M, Garcia-Closas Montserrat, Gaudet Mia M, Haiman Christopher A, Hazra Aditi, Henderson Brian, Hoover Robert, Hüsing Anika, Johansson Mattias, Kaaks Rudolf, Khaw Kay-Tee, Kolonel Laurence N, Le Marchand Loic, Lissowska Jolanta, Lund Eiliv, McCullough Marjorie L, Peplonska Beata, Riboli Elio, Sacerdote Carlotta, Sánchez María-José, Tjønneland Anne, Trichopoulos Dimitrios, van Gils Carla H, Yeager Meredith, Kraft Peter, Hunter David J, Ziegler Regina G, Willett Walter C
Abstract excerpt
BACKGROUND: Dietary and circulating carotenoids have been inversely associated with breast cancer risk, but observed associations may be due to confounding. Single-nucleotide polymorphisms (SNPs) in β-carotene 15,15'-monooxygenase 1 (BCMO1), a gene encoding the enzyme involved in the first step of synthesizing vitamin A from dietary carotenoids, have been associated with circulating carotenoid concentrations and...
Read the complete abstract on PubMed