Article
Genome-wide methylation changes in the brains of suicide completers.
The American journal of psychiatry - 1 May 2013
Labonté Benoit, Suderman Matt, Maussion Gilles, Lopez Juan Pablo, Navarro-Sánchez Luis, Yerko Volodymyr, Mechawar Naguib, Szyf Moshe, Meaney Michael J, Turecki Gustavo
Abstract excerpt
OBJECTIVE: Gene expression changes have been reported in the brains of suicide completers. More recently, differences in promoter DNA methylation between suicide completers and comparison subjects in specific genes have been associated with these changes in gene expression patterns, implicating DNA methylation alterations as a plausible component of the pathophysiology of suicide. The authors used a genome-wide...
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