Article
Single-nucleotide polymorphisms in genes encoding toll-like receptor -2, -3, -4, and -9 in case-control study with breast cancer.
Genetic testing and molecular biomarkers - 1 Dec 2009
Etokebe Godfrey E, Knezević Jelena, Petricević Branka, Pavelić Jasminka, Vrbanec Damir, Dembić Zlatko
Abstract excerpt
BACKGROUND: Genetic susceptibility to cancer is multifactorial, and it is known that impairment of the immune system could contribute to risk for getting cancer. AIM OF THE STUDY: Single-nucleotide polymorphisms (SNPs) of Toll-like receptor (TLR) 2, TLR3, TLR4, and TLR9 genes, which are important for innate immunity, were analyzed for the association with breast cancer. METHODS: The SNPs comprised TLR2...
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