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Article

Glutamate transporter expression and function in a striatal neuronal model of Huntington's disease.

Neurochemistry international - 1 Jun 2013

Petr Geraldine T, Bakradze Ekaterina, Frederick Natalie M, Wang Jianlin, Armsen Wencke, Aizenman Elias, Rosenberg Paul A

Abstract excerpt

Excitotoxicity may contribute to the pathogenesis of Huntington's disease. High affinity Na+ dependent glutamate transporters, residing in the plasma membrane, clear glutamate from the extracellular space and are the primary means of protection against excitotoxicity. Many reports suggest that Huntington's disease is associated with a decrease in the expression and function of glutamate transporters. We studied...

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Identifiers

PMID: 23507328
DOI: 10.1016/j.neuint.2013.02.026
PMCID: PMC3653299

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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