Article
Estrogen receptor alpha single nucleotide polymorphism as predictor of diabetes type 2 risk in hypogonadal men.
The aging male : the official journal of the International Society for the Study of the Aging Male - 1 Jun 2013
Linnér Carl, Svartberg Johan, Giwercman Aleksander, Giwercman Yvonne Lundberg
Abstract excerpt
Estradiol (E2) is, apart from its role as a reproductive hormone, also important for cardiac function and bone maturation in both genders. It has also been shown to play a role in insulin production, energy expenditure and in inducing lipolysis. The aim of the study was to investigate if low circulating testosterone or E2 levels in combination with variants in the estrogen receptor alpha (ESR1) and estrogen...
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