Article
Definition of the unique human extraocular muscle allotype by expression profiling.
Physiological genomics - 11 Aug 2005
Fischer M Dominik, Budak Murat T, Bakay Marina, Gorospe J Rafael, Kjellgren D, Pedrosa-Domellöf F, Hoffman Eric P, Khurana Tejvir S
Abstract excerpt
The extraocular muscles (EOMs) are a unique group of specialized muscles that are anatomically and physiologically distinct from other skeletal muscles. Perhaps the most striking characteristic of the EOMs is their differential sensitivity to disease. EOMs are spared in Duchenne's muscular dystrophy (DMD) despite widespread involvement of other skeletal muscles. Conversely, they are early and prominent targets in...
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