Article
Adcyap1r1 genotype, posttraumatic stress disorder, and depression among women exposed to childhood maltreatment.
Depression and anxiety - 1 Mar 2013
Uddin Monica, Chang Shun-Chiao, Zhang Chao, Ressler Kerry, Mercer Kristina B, Galea Sandro, Keyes Katherine M, McLaughlin Katie A, Wildman Derek E, Aiello Allison E, Koenen Karestan C
Abstract excerpt
BACKGROUND: A growing literature indicates that genetic variation, in combination with adverse early life experiences, shapes risk for later mental illness. Recent work also suggests that molecular variation at the ADCYAP1R1 locus is associated with posttraumatic stress disorder (PTSD) in women. We sought to test whether childhood maltreatment (CM) interacts with ADCYAP1R1 genotype to predict PTSD in women....
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