Association of PTPN22-C1858T Polymorphism With Susceptibility to Mycobacterium tuberculosis and Mycobacterium leprae Infection: A Meta-Analysis.

doi:10.3389/fimmu.2021.592841

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Article

Association of PTPN22-C1858T Polymorphism With Susceptibility to Mycobacterium tuberculosis and Mycobacterium leprae Infection: A Meta-Analysis.

Frontiers in immunology - 1 Jan 2021

Li Shuping, Wang Xiaohua, Zhao Yuming, Yang Juan, Cui Tianjiao, Zhao Zhizhuang Joe, Chen Yun, Zheng Zhihua

Abstract excerpt

It was previously published that single-nucleotide polymorphism rs2476601 (PTPN22 [protein tyrosine phosphatase non-receptor type 22]-C1858T) might be related to increased sensibility to Mycobacterium tuberculosis and M. leprae infection. However, the results were inconclusive despite a high degree of similarity between both parameters. Herein, we carried out this meta-analysis to systematically summarize and...

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PMID: 33717071
DOI: 10.3389/fimmu.2021.592841
PMCID: PMC7950544

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