Article
XRCC1 and XPD DNA repair gene polymorphisms: a potential risk factor for glaucoma in the Pakistani population.
Molecular vision - 1 Jan 2011
Yousaf Sajeela, Khan Muhammad Imran, Micheal Shazia, Akhtar Farah, Ali Syeda Hafiza Benish, Riaz Moeen, Ali Mahmood, Lall Pramila, Waheed Nadia Khalida, den Hollander Anneke I, Ahmed Asifa, Qamar Raheel
Abstract excerpt
PURPOSE: The present study was designed to determine the association of polymorphisms of the DNA repair genes X-ray cross-complementing group 1 (XRCC1) (c.1316G>A [rs25487]) and xeroderma pigmentosum complementation group D (XPD) (c.2298A>C [rs13181]) with primary open-angle glaucoma (POAG) and primary closed-angle glaucoma (PCAG). METHODS: In this prospective case-control study, polymerase chain...
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