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Article

Genetic polymorphism of hOGG1 and risk of pterygium in Chinese.

Eye (London, England) - 1 Jun 2004

Kau H-C, Tsai C-C, Hsu W-M, Liu J-H, Wei Y-H

Abstract excerpt

PURPOSE: Ultraviolet irradiation is known to cause oxidative DNA damage and is thought to be a major factor implicated in the pathogenesis of pterygium. The highly mutagenic 8-hydroxy-2'-deoxyguanosine, a marker for the evaluation of photo-oxidative DNA damage, can be repaired by human 8-oxoguanine glycosylase I (hOGG1). A transition of C to G at nucleotide position 1245 in exon 7 of the hOGG1 gene is associated...

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PMID: 14716324
DOI: 10.1038/sj.eye.6700738

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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