Article
Vitamin K-dependent proteins GAS6 and Protein S and TAM receptors in patients of systemic lupus erythematosus: correlation with common genetic variants and disease activity.
Arthritis research & therapy - 12 Mar 2013
Recarte-Pelz Pedro, Tàssies Dolors, Espinosa Gerard, Hurtado Begoña, Sala Núria, Cervera Ricard, Reverter Joan Carles, de Frutos Pablo García
Abstract excerpt
INTRODUCTION: Growth arrest-specific gene 6 protein (GAS6) and protein S (ProS) are vitamin K-dependent proteins present in plasma with important regulatory functions in systems of response and repair to damage. They interact with receptor tyrosine kinases of the Tyro3, Axl and MerTK receptor tyrosine kinase (TAM) family, involved in apoptotic cell clearance (efferocytosis) and regulation of the innate immunity....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.