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Article

Human vitamin K-dependent GAS6: gene structure, allelic variation, and association with stroke.

Human mutation - 1 May 2004

Muñoz Xavier, Sumoy Lauro, Ramírez-Lorca Reposo, Villar José, de Frutos Pablo García, Sala Núria

Abstract excerpt

The product of the growth arrest-specific gene 6 (GAS6), a ligand for the Axl, Sky, and Mer tyrosine kinase receptors, is a vitamin K-dependent protein, structurally related to anticoagulant protein S. Gas6-deficient mice are protected against thrombosis, demonstrating the importance of this protein in the cardiovascular system. The present study was aimed at determining the human GAS6 intron-exon structure and...

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Source

Identifiers

PMID: 15108283
DOI: 10.1002/humu.20025

Genes

GAS6

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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