Article
Genetic polymorphism of the growth arrest-specific 6 gene is associated with cutaneous vasculitis in Taiwanese patients with systemic lupus erythematosus.
Clinical rheumatology - 1 Oct 2012
Wu Chien-Sheng, Hu Chung-Yi, Chan Cheng-Ju, Chang Sheng-Kai, Hsu Ping-Ning
Abstract excerpt
The growth arrest-specific 6 (GAS6) gene product participates in platelet activation and granulocyte interaction with the endothelium. Our case-control study aimed to determine whether polymorphism of GAS6 was associated with predisposing risk or specific clinical manifestations of systemic lupus erythematosus (SLE). Two of the single-nucleotide polymorphisms (SNPs) of the GAS6 gene, GAS6 834 + 7G/A (rs8191974)...
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