Article
EGFR mutations in lung cancer: from tissue testing to liquid biopsy.
Future oncology (London, England) - 1 Jan 2015
Fenizia Francesca, De Luca Antonella, Pasquale Raffaella, Sacco Alessandra, Forgione Laura, Lambiase Matilde, Iannaccone Alessia, Chicchinelli Nicoletta, Franco Renato, Rossi Antonio, Morabito Alessandro, Rocco Gaetano, Piccirillo Maria Carmela, Normanno Nicola
Abstract excerpt
ABSTRACT The presence of EGFR mutations predicts the sensitivity to EGF receptor (EGFR)-tyrosine kinase inhibitors in a molecularly defined subset of non-small-cell lung carcinoma (NSCLC) patients. For this reason, EGFR testing of NSCLC is required to provide personalized treatment options and better outcomes for NSCLC patients. As surgery specimens are not available in the majority of NSCLC, other currently...
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