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Article

Low-density lipoprotein receptor-related protein 5 gene polymorphisms and genetic susceptibility to abdominal aortic aneurysm.

Journal of vascular surgery - 1 Oct 2013

Galora Silvia, Saracini Claudia, Palombella Anna Maria, Pratesi Giovanni, Pulli Raffaele, Pratesi Carlo, Abbate Rosanna, Giusti Betti

Abstract excerpt

BACKGROUND: Previous data showed decreased low-density lipoprotein receptor-related protein 5 (LRP5) gene expression in peripheral blood cells of abdominal aortic aneurysm (AAA) patients and an association between decreased expression of LRP5 and increased lipoprotein (a) [Lp(a)] levels in AAA. LRP5 gene is involved in bone, lipid, and glucose metabolism, and experimental studies showed that atherosclerotic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23490293
DOI: 10.1016/j.jvs.2012.11.092

Genes

LRP5

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