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Article

Differential expression and tumor necrosis factor-mediated regulation of TNFRSF11b/osteoprotegerin production by human melanomas.

Pigment cell & melanoma research - 1 Jul 2013

Oliver Janine L, Alexander Matthew P, Norrod Allison G, Mullins Irene M, Mullins David W

Abstract excerpt

Tumors escape host immune responses, in part, through the release of immunomodulatory factors and decoy receptors into their microenvironment. Several cancers express surface-bound and soluble members of the tumor necrosis factor (TNF) receptor superfamily, including TNFRSF11b/osteoprotegerin (OPG). In its physiologic role, OPG regulates bone remodeling through competition for osteoclast-activating cytokines and...

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Source

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Identifiers

PMID: 23490134
DOI: 10.1111/pcmr.12091
PMCID: PMC3964368

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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