Article
The contribution of the C-824T tyrosine hydroxylase polymorphism to the prevalence of hypertension in a South African cohort: the SABPA study.
Clinical and experimental hypertension (New York, N.Y. : 1993) - 1 Jan 2013
van Deventer Cindy A, Louw Roan, van der Westhuizen Francois H, Vorster Chris B, Malan Leoné
Abstract excerpt
The C-824T single nucleotide polymorphism in the promoter region of the tyrosine hydroxylase gene has been associated with hypertension. It is well documented that African South Africans exhibit a higher prevalence of hypertension than Caucasians. However, the possible role of this mutation on 24-hour ambulatory blood pressure (AMBP) has not been investigated in African South Africans. Blood samples of 409 South...
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