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Article

Fibrocytes develop outside the kidney but contribute to renal fibrosis in a mouse model.

Kidney international - 1 Jul 2013

Reich Barbara, Schmidbauer Kathrin, Rodriguez Gomez Manuel, Johannes Hermann Fabian, Göbel Nicole, Brühl Hilke, Ketelsen Isabel, Talke Yvonne, Mack Matthias

Abstract excerpt

Collagen-producing bone marrow-derived cells (fibrocytes) have been detected in animal models and patients with fibrotic diseases. In vitro data suggest that they develop from monocytes with the help of accessory cells and profibrotic soluble factors. Using a mouse model of renal fibrosis, unilateral ureteral obstruction, we found the number of circulating fibrocytes was not reduced when monocytes were depleted...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23486523
DOI: 10.1038/ki.2013.84

Genes

CCR2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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