Article
Therapeutic Vaccination Expands and Improves the Function of the HIV-Specific Memory T-Cell Repertoire
12 Mar 2013
Abstract excerpt
BACKGROUND: The licensing of herpes zoster vaccine has demonstrated that therapeutic vaccination can help control chronic viral infection. Unfortunately, human trials of immunodeficiency virus (HIV) vaccine have shown only marginal efficacy. METHODS: In this double-blind study, 17 HIV-infected individuals with viral loads of <50 copies/mL and CD4(+) T-cell counts of >350 cells/µL were randomly assigned to the...
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