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Article

Characterization of a flatworm inositol (1,4,5) trisphosphate receptor (IP₃R) reveals a role in reproductive physiology.

Cell calcium - 1 Jan 2000

Zhang Dan, Liu Xiaolong, Chan John D, Marchant Jonathan S

Abstract excerpt

Inositol 1,4,5-trisphosphate receptors (IP₃Rs) are intracellular Ca²⁺ channels that elevate cytoplasmic Ca²⁺ in response to the second messenger IP3. Here, we describe the identification and in vivo functional characterization of the planarian IP₃R, the first intracellular Ca²⁺ channel to be defi...

Topics

Amino Acid Sequence
Animals
Arginine
Cells, Cultured
Helminth Proteins
Inositol 1,4,5-Trisphosphate
Inositol 1,4,5-Trisphosphate Receptors
Molecular Sequence Data
Mutation
Peptide Fragments
Phylogeny
Planarians

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Protein Binding

Reproduction

Transgenes

Source

Open in PubMed Open full text

Identifiers

PMID: 23481272
DOI: 10.1016/j.ceca.2013.01.003
PMCID: PMC3665645

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-23481272-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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