Article
A diverse family of inositol 5-phosphatases playing a role in growth and development in Dictyostelium discoideum.
The Journal of biological chemistry - 21 Feb 2003
Loovers Harriet M, Veenstra Kees, Snippe Helena, Pesesse Xavier, Erneux Christophe, van Haastert Peter J M
Abstract excerpt
Inositol phosphate-containing molecules play an important role in a broad range of cellular processes. Inositol 5-phosphatases participate in the regulation of these signaling molecules. We have identified four inositol 5-phosphatases in Dictyostelium discoideum, Dd5P1-4, showing a high diversity in domain composition. Dd5P1 possesses only a inositol 5-phosphatase catalytic domain. An unique domain composition is...
Topics
- Amino Acid Sequence
- Animals
- Blotting, Northern
- Dictyostelium
- Genetic Variation
- Humans
- Inositol Polyphosphate 5-Phosphatases
- Kinetics
- Molecular Sequence Data
- Phosphoric Monoester Hydrolases
- Sequence Alignment
- Sequence Homology, Amino Acid
- Substrate Specificity