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Article

Nuclear hormone receptors in parasitic Platyhelminths

27 Aug 2019

Abstract excerpt

Nuclear receptors (NRs) belong to a large protein superfamily which includes intracellular receptors for secreted hydrophobic signal molecules, such as steroid hormones and thyroid hormones. They regulate development and reproduction in metazoans by binding to the promoter region of their target gene to activate or repress mRNA synthesis. Isolation and characterization of NRs in the parasitic trematode...

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PMID: 31470045
DOI: 10.1016/j.molbiopara.2019.111218

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