Article

Profiling G protein-coupled receptors of <i>Fasciola hepatica</i> identifies orphan rhodopsins unique to phylum Platyhelminthes

2017-10-22

Abstract excerpt

G protein-coupled receptors (GPCRs) are established drug targets. Despite their considerable appeal as targets for next-generation anthelmintics, poor understanding of their diversity and function in parasitic helminths has thwarted progress towards GPCR-targeted anti-parasite drugs. This study facilitates GPCR research in the liver fluke, Fasciola hepatica , by generating the first profile of GPCRs from the F....

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Literature Corpus work: 7604d83f-7012-5114-b70f-324d2ac66ba7
DOI: 10.1101/207316

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