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Article

Suppression of host p53 is critical for Plasmodium liver-stage infection.

Cell reports - 28 Mar 2013

Kaushansky Alexis, Ye Albert S, Austin Laura S, Mikolajczak Sebastian A, Vaughan Ashley M, Camargo Nelly, Metzger Peter G, Douglass Alyse N, MacBeath Gavin, Kappe Stefan H I

Abstract excerpt

Plasmodium parasites infect the liver and replicate inside hepatocytes before they invade erythrocytes and trigger clinical malaria. Analysis of host signaling pathways affected by liver-stage infection could provide critical insights into host-pathogen interactions and reveal targets for intervention. Using protein lysate microarrays, we found that Plasmodium yoelii rodent malaria parasites perturb hepatocyte...

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Identifiers

PMID: 23478020
DOI: 10.1016/j.celrep.2013.02.010
PMCID: PMC3619000

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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