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Malaria parasite liver stages render host hepatocytes susceptible to mitochondria-initiated apoptosis

8 Aug 2013

Abstract excerpt

Intracellular eukaryotic parasites and their host cells constitute complex, coevolved cellular interaction systems that frequently cause disease. Among them, Plasmodium parasites cause a significant health burden in humans, killing up to one million people annually. To succeed in the mammalian host after transmission by mosquitoes, Plasmodium parasites must complete intracellular replication within hepatocytes...

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Identifiers

PMID: 23928701
DOI: 10.1038/cddis.2013.286

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