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Article

Impact of interaction of cigarette smoking with angiotensin-converting enzyme polymorphisms on end-stage renal disease risk in a Han Chinese population.

Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Mar 2015

Yang Hsin-Yi, Lu Kuo-Cheng, Fang Wen-Hui, Lee Herng-Sheng, Wu Chia-Chao, Huang Yi-Hsuan, Lin Yuh-Feng, Kao Sen-Yeong, Lai Ching-Huang, Chu Chi-Ming, Su Sui-Lung

Abstract excerpt

BACKGROUND: Several polymorphisms in the angiotensin-converting enzyme (ACE) and ACE2 genes are associated with the development of end-stage renal disease (ESRD). Certain genetic polymorphisms may modify the deleterious effects of environmental factors such as cigarette smoking and may also modify the inherited risk. We investigated the association of six ACE and ACE2 polymorphisms with ESRD to determine whether...

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Source

Identifiers

PMID: 23477970
DOI: 10.1177/1470320313481837

Genes

ACE
ACE2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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