Article
Oligosaccharide Y specific monoclonal antibody and its isotype switch variants.
Hybridoma - 1 Apr 1990
Steplewski Z, Blaszczyk-Thurin M, Lubeck M, Loibner H, Scholz D, Koprowski H
Abstract excerpt
Isotype switch variants of the IgG3 secreting hybridoma BR55-2 were developed with gamma 1, gamma 2b and gamma 2a heavy chains. The variants have the same affinity for antigen and expected affinities for the Fc receptor. The Y antigen defined by MAb BR55-2 has a restricted distribution to breast, colorectal, pancreatic, gastric and small cell lung carcinomas. The MAb BR55-2 also bound to prostatic and laryngeal...
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