Article
A Serratia marcescens PigP homolog controls prodigiosin biosynthesis, swarming motility and hemolysis and is regulated by cAMP-CRP and HexS.
PloS one - 1 Jan 2013
Shanks Robert M Q, Lahr Roni M, Stella Nicholas A, Arena Kristin E, Brothers Kimberly M, Kwak Daniel H, Liu Xinyu, Kalivoda Eric J
Abstract excerpt
Swarming motility and hemolysis are virulence-associated determinants for a wide array of pathogenic bacteria. The broad host-range opportunistic pathogen Serratia marcescens produces serratamolide, a small cyclic amino-lipid, that promotes swarming motility and hemolysis. Serratamolide is negatively regulated by the transcription factors HexS and CRP. Positive regulators of serratamolide production are unknown....
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