Article
Stabilization of actin bundles by a dynamin 1/cortactin ring complex is necessary for growth cone filopodia.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 6 Mar 2013
Yamada Hiroshi, Abe Tadashi, Satoh Ayano, Okazaki Nana, Tago Shota, Kobayashi Kinue, Yoshida Yumi, Oda Yoshiya, Watanabe Masami, Tomizawa Kazuhito, Matsui Hideki, Takei Kohji
Abstract excerpt
Dynamin GTPase, a key molecule in endocytosis, mechanically severs the invaginated membrane upon GTP hydrolysis. Dynamin functions also in regulating actin cytoskeleton, but the mechanisms are yet to be defined. Here we show that dynamin 1, a neuronal isoform of dynamin, and cortactin form ring c...
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