Copy number variation of the antimicrobial-gene, defensin beta 4, is associated with susceptibility to cervical cancer.

doi:10.1038/jhg.2013.7

Article

Copy number variation of the antimicrobial-gene, defensin beta 4, is associated with susceptibility to cervical cancer.

Journal of human genetics - 1 May 2013

Abe Shuhei, Miura Kiyonori, Kinoshita Akira, Mishima Hiroyuki, Miura Shoko, Yamasaki Kentaro, Hasegawa Yuri, Higashijima Ai, Jo Ozora, Sasaki Kensaku, Yoshida Atsushi, Yoshiura Koh-ichiro, Masuzaki Hideaki

Abstract excerpt

The aim of this study was to investigate association between copy number variation of the defensin beta 4 gene (DEFB4) and susceptibility to cervical cancer in a population at high risk of persistent oncogenic human papillomavirus (HPV) infection. The study subjects comprised 204 women with cervical cancer, a population having a high risk of persistent oncogenic HPV infection (cervical cancer group), and 200...

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Copy number variation of the antimicrobial-gene, defensin beta 4, is associated with susceptibility to cervical cancer.

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