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Gene Cloning and Characterization of MdeA, a Novel Multidrug Efflux Pump in Streptococcus mutans

25 Mar 2013

Abstract excerpt

Multidrug resistance, especially multidrug efflux mechanisms that extrude structurally unrelated cytotoxic compounds from the cell by multidrug transporters, is a serious problem and one of the main reasons for the failure of therapeutic treatment of infections by pathogenic microorganisms as well as of cancer cells. Streptococcus mutans is considered one of the primary causative agents of dental caries and...

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PMID: 23462018
DOI: 10.4014/jmb.1301.01028

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