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Article

Functional study of the novel multidrug efflux pump KexD from Klebsiella pneumoniae.

Gene - 1 May 2012

Ogawa Wakano, Onishi Motoyasu, Ni Ruiting, Tsuchiya Tomofusa, Kuroda Teruo

Abstract excerpt

We cloned a gene, kexD, that provides a multidrug-resistant phenotype from multidrug-resistant Klebsiella pneumoniae MGH78578. The deduced amino acid sequence of KexD is similar to that of the inner membrane protein, RND-type multidrug efflux pump. Introduction of the kexD gene into Escherichia coli KAM32 resulted in a MIC that was higher for erythromycin, novobiocin, rhodamine 6G, tetraphenylphosphonium...

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Identifiers

PMID: 22391093
DOI: 10.1016/j.gene.2012.02.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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