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Article

Changes in kinesin expression in the CNS of mice with dynein heavy chain 1 mutation.

Acta biochimica Polonica - 1 Jan 2013

Kuźma-Kozakiewicz Magdalena, Kaźmierczak Beata, Usarek Ewa, Barańczyk-Kuźma Anna

Abstract excerpt

Dysfunction of fast axonal transport, vital for motor neurons, may lead to neurodegeneration. Anterograde transport is mediated by N-kinesins (KIFs), while retrograde transport by dynein 1 and, to a minor extent, by C-kinesins. In our earlier studies we observed changes in expression of N- and C-kinesins (KIF5A, 5C, C2) in G93ASOD1-linked mouse model of motor neuron degeneration. In the present work we analyze...

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Share to Central Nervous System
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23460941

Genes

SOD1
KIFC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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