Article
The variability of the 16S rRNA gene in bacterial genomes and its consequences for bacterial community analyses.
PloS one - 1 Jan 2013
Větrovský Tomáš, Baldrian Petr
Abstract excerpt
16S ribosomal RNA currently represents the most important target of study in bacterial ecology. Its use for the description of bacterial diversity is, however, limited by the presence of variable copy numbers in bacterial genomes and sequence variation within closely related taxa or within a genome. Here we use the information from sequenced bacterial genomes to explore the variability of 16S rRNA sequences and...
Topics
- Computer Simulation
- DNA, Bacterial
- Ecosystem
- Gene Dosage
- Genetic Variation
- Genome Size
- Genome, Bacterial
- Phylogeny
- RNA, Ribosomal, 16S
- Sequence Analysis, DNA
- Soil Microbiology