Article
Listeria monocytogenes alters mast cell phenotype, mediator and osteopontin secretion in a listeriolysin-dependent manner.
PloS one - 1 Jan 2013
Jobbings Catherine E, Sandig Hilary, Whittingham-Dowd Jayde K, Roberts Ian S, Bulfone-Paus Silvia
Abstract excerpt
Whilst mast cells participate in the immune defence against the intracellular bacterium Listeria monocytogenes, there is conflicting evidence regarding the ability of L. monocytogenes to infect mast cells. It is known that the pore-forming toxin listeriolysin (LLO) is important for mast cell activation, degranulation and the release of pro-inflammatory cytokines. Mast cells, however, are a potential source of a...
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