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Article

pH-dependent perforation of macrophage phagosomes by listeriolysin O from Listeria monocytogenes.

The Journal of experimental medicine - 6 Oct 1997

Beauregard K E, Lee K D, Collier R J, Swanson J A

Abstract excerpt

The pore-forming toxin listeriolysin O (LLO) is a major virulence factor implicated in escape of Listeria monocytogenes from phagocytic vacuoles. Here we describe the pH-dependence of vacuolar perforation by LLO, using the membrane-impermeant fluorophore 8-hydroxypyrene-1,3,6-trisulfonic acid (HP...

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Identifiers

PMID: 9314564
DOI: 10.1084/jem.186.7.1159
PMCID: PMC2199064

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-9314564-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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