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Article

Characterization of Osterix protein stability and physiological role in osteoblast differentiation.

PloS one - 1 Jan 2013

Peng Yanyan, Shi Kaikai, Wang Lintao, Lu Jianlei, Li Hongwei, Pan Shiyang, Ma Changyan

Abstract excerpt

Osterix (Osx/SP7) is a C2H2 zinc finger-containing transcription factor of the SP gene family. Osx knockout mice indicate that the gene plays an essential role in osteoblast differentiation and bone formation. However, the mechanisms involved in the regulation of Osx are still poorly understood. Here, we report a novel post-translational mechanism for the regulation of Osx in mammalian cells. We found that the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23457570
DOI: 10.1371/journal.pone.0056451
PMCID: PMC3574093

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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