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Gene Therapy of Cancer Based on Interleukin 12

30 Nov 2005

Abstract excerpt

Tumor formation and growth depends mainly on the inability of the organism to elicit a potent immune response, and on the formation of new blood vessels that enable tumor nutrition. Interleukin-12 (IL-12) therapy can target both processes. And IL-12-based gene therapy may restrict IL-12 production to the relevant site in order to obtain enhanced antitumor activity and reduced toxicity. In the clinical setting,...

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Identifiers

PMID: 16457647
DOI: 10.2174/156652305774964712

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