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Article

Prion infectivity in the spleen of a PRNP heterozygous individual with subclinical variant Creutzfeldt-Jakob disease.

Brain : a journal of neurology - 1 Apr 2013

Bishop Matthew T, Diack Abigail B, Ritchie Diane L, Ironside James W, Will Robert G, Manson Jean C

Abstract excerpt

Blood transfusion has been identified as a source of human-to-human transmission of variant Creutzfeldt-Jakob disease. Three cases of variant Creutzfeldt-Jakob disease have been identified following red cell transfusions from donors who subsequently developed variant Creutzfeldt-Jakob disease and...

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Source

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Identifiers

PMID: 23449776
DOI: 10.1093/brain/awt032
PMCID: PMC3613713

Genes

PRNP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23449776-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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