Article
Functional relevance of genetic variations of endothelial nitric oxide synthase and vascular endothelial growth factor in diabetic coronary microvessel dysfunction.
Clinical and experimental pharmacology & physiology - 1 Apr 2013
Joshi Mandar S, Berger Philip J, Kaye David M, Pearson James T, Bauer John A, Ritchie Rebecca H
Abstract excerpt
The prevalence of type 1 diabetes (T1D) is increasing worldwide and is associated with significant microvessel complications, of which nephropathy, retinopathy and neuropathy are the most commonly studied. Although clinically evident microvascular complications of diabetes are rarely seen in childhood, early vascular abnormalities develop during childhood and accelerate during puberty. Vascular endothelial growth...
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