Article
GDF9 modulates the reproductive and tumor phenotype of female inha-null mice.
Biology of reproduction - 1 Apr 2013
Myers Michelle, Mansouri-Attia Nadera, James Rebecca, Peng Jia, Pangas Stephanie A
Abstract excerpt
Intraovarian factors play important roles in coordinating germ cell and somatic cell growth in the ovary. Prior to the onset of gonadotropin stimulation and reproductive cyclicity, follicle development is dependent upon locally produced growth factors, such as the transforming growth factor beta family members inhibin, activin, and GDF9. In the absence of inhibin in prepubertal mice (Inha(-/-)), there are marked...
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