Article
Variation in presentation and presence of DNA adducts and p53 mutations in patients with endemic nephropathy--an environmental form of the aristolochic acid nephropathy.
Kidney & blood pressure research - 1 Jan 2013
Karanović Sandra, Lela Ivana Vuković, Jelaković Bojan, Dickman Kathleen G, Peić Anamarija Kovač, Dittrich Damir, Knežević Matej, Matijević Vesna, Fernandes Andrea S, Miller Frederick
Abstract excerpt
BACKGROUND: Endemic nephropathy (EN) and associated urothelial cell cancers (UUC) are an environmental form of aristolochic acid nephropathy where the most probable rout of ingestion of aristolochic acid (AA) was made by bread contaminated with AA, leading to chronic dietary intoxication. Clinical courses of three members of the same family, similarly exposed to toxin, who exhibited different clinical courses of...
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