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Mast Cells and IgE: From History to Today

1 Jan 2013

Abstract excerpt

Role of mast cells in allergy had remained undetermined until the discovery of IgE in 1966. Then, IgE purified from many Liters of plasma, which had been donated from a patient with fatal myeloma, was distributed to researchers all over the world, and thus accelerated exploring the mechanisms involved in allergic reactions, particularly about the role of mast cells and basophils in the IgE-mediated reactions....

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PMID: 23439053
DOI: 10.2332/allergolint.13-rai-0537

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