Article
Growth differentiation factor 5 regulation in bone regeneration.
Current pharmaceutical design - 1 Jan 2013
Jin Li, Li Xudong
Abstract excerpt
Growth differentiation factor 5 (GDF5) is a member of the bone morphogenic protein (BMP) family and plays critical roles in organ development processes including bone, cartilage, ligament, and joint formation. GDF5 is expressed in the cartilage primordium in the early limb development, and in the interzone of joint formation sites. GDF5 is also observed in adult tissue and cell lines. This spatialtemporal...
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