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Article

Virulence of Burkholderia mallei Quorum-Sensing Mutants

20 Feb 2013

Abstract excerpt

Many Proteobacteria use acyl-homoserine lactone-mediated quorum-sensing (QS) to activate specific sets of genes as a function of cell density. QS often controls the virulence of pathogenic species, and in fact a previous study indicated that QS was important for Burkholderia mallei mouse lung infections. To gain in-depth information on the role of QS in B. mallei virulence, we constructed and characterized a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 23429539
DOI: 10.1128/iai.00048-13

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