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Article

A polymorphism in metallothionein 1A (MT1A) is associated with cadmium-related excretion of urinary beta 2-microglobulin.

Toxicology and applied pharmacology - 15 Dec 2012

Lei Lijian, Chang Xiuli, Rentschler Gerda, Tian Liting, Zhu Guoying, Chen Xiao, Jin Taiyi, Broberg Karin

Abstract excerpt

OBJECTIVES: Cadmium (Cd) toxicity of the kidney varies between individuals despite similar exposure levels. In humans Cd is mainly bound to metallothioneins (MT), which scavenge its toxic effects. Here we analyzed whether polymorphisms in MT genes MT1A and MT2A influence Cd-related kidney damage....

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Identifiers

PMID: 22995156
DOI: 10.1016/j.taap.2012.09.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22995156-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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